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It seems that you're in Germany. We have a dedicated site for Germany. This highly informative monograph offers a comprehensive and interdisciplinary reference guide for the management and treatment of the whole spectrum of painful tears in the anus and anal canal. Based upon a systematic review of all relevant papers on the topic since , it addresses primary, acute and chronic anal fissures — providing a new definition of the last form — and secondary anal fissures in detail, particularly their medical history, etiology, signs and symptoms, medical findings, therapy and its evaluation, and differential diagnosis. The book also covers all available evidence-based therapeutic strategies. As such, it will appeal to a wide readership, from proctologists and surgeons to gynecologists, urologists, dermatologists and gastroenterologists.
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AIM: Six Phase III randomized trials have determined the effectiveness of chemoradiotherapy as primary treatment for anal squamous cell carcinoma ASCC , but outcomes reported in these trials varied widely, hindering evidence synthesis. To improve reporting in all future trials, we aim to develop a core outcomes set COS. As the first stage of COS development, we undertook a systematic review to summarize the outcomes reported in studies evaluating chemoradiotherapy for ASCC. Outcomes and accompanying definitions were extracted verbatim and categorized into domains. We collapsed these terms into 86 standardized outcomes and five domains: survival; disease activity; life impact [including quality of life QoL ]; delivery of care; and toxicity.
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Marcia Cross has discussed her experience with anal cancer in the hopes of de-stigmatising the disease and raising awareness about ways it can be prevented. In November , the actress was at her doctor for an annual rectal exam when a cancerous mass was discovered in her anus - almost 10 years after her husband Tom Mahoney was treated for throat cancer. According to doctors, the cancers were likely caused by the same type of human papillomavirus or HPV , a sexually transmitted disease. Do you have to then also feel ashamed like you did something bad, you know, because it took up residence in your anus? In addition to discussing the disease so that others are not embarrassed talking about rectal exams and treatment, Cross also wants to inform people that anal cancer is preventable - as the Centre for Disease Control and Prevention CDC states 90 per cent of anal cancer cases are caused by HPV, which can also cause genital, cervical and throat cancers, but the types of HPV that commonly cause cancer are preventable with the vaccine.

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